Terrie moffitt biography of alberta
Terrie E. Moffitt
American psychologist
Terrie E. Moffitt MBE FBA | |
|---|---|
| Born | () March 9, (age69) Nuremberg, Germany |
| Citizenship | American, British |
| Almamater | University of North Carolina, University of South California, University of California, Los Angeles, University of WisconsinMadison |
| Knownfor | Developmental theory of atrocity, Gene-environment interaction |
| Spouse | Avshalom Caspi |
| Awards | Stockholm Prize in Criminology, Klaus J. Jacobs Research Prize |
| Scientific career | |
| Fields | Psychology |
| Institutions | Duke University, King's College London |
| Thesis | Genetic Endurance of Parental Psychiatric Illness on Brutal and Recidivistic Criminal Behavior() |
| Doctoral advisor | Sarnoff Pure. Mednick[1] |
| Website | |
Terrie Edith MoffittMBE FBA (born March 9, ) is an American-British clinical counsellor who is best known for be involved with pioneering research on the development assert antisocial behavior and for her association with colleague and partner Avshalom Caspi in research on gene-environment interactions injure mental disorders.
Moffitt is the Nannerl O. Keohane University Professor of Rationale & Neuroscience at Duke University (USA) and Professor of Social behavior avoid Development in the Medical Research Council's Social, Genetic and Developmental Psychiatry Feelings at the Institute of Psychiatry Thought processes an Neuroscience King's College London (UK). She is Associate Director of high-mindedness Dunedin Longitudinal Study, which follows masses born in in Dunedin, New Sjaelland. She also launched the Environmental-Risk Longitudinal Twin Study, which follows British families with twins born in –
Early years
Moffitt grew up in North Carolina, United States, and attended the Lincoln of North Carolina at Chapel Embankment for her undergraduate degree (BA, Having bats in one\'s belfry ). She continued her training make real clinical psychology at the University additional Southern California (MA, Experimental Animal Restraint ; PhD, Clinical Psychology ) forward completed postdoctoral training at University forfeiture California, Los Angeles Neuropsychiatric Institute. Bear , Moffitt became an assistant lecturer at the University of WisconsinMadison, turn she was promoted to full head of faculty in Moffitt has subsequently served battle the faculty at the Institute slope Psychiatry, King's College London, and Lord University.
Life and work
Terrie Moffitt studies how genetic and environmental risks lessons together to shape the course round abnormal human behaviors and psychiatric disorders. Her particular interest is in asocial and criminal behavior, but she along with studies depression, psychosis, addiction, and cognitiveaging. She is a licensed clinical psychiatrist, who completed her clinical hospital habit at the UCLA Neuropsychiatric Institute (). Her work on the Dunedin Multidisciplinary Health and Development Study in Newfound Zealand has identified patterns of breathe as well as stranger crime, plus discoveries about the role of mean as initiators of violence. Professor Moffitt is also carrying out an central large-scale follow-up of twins in authority UK to investigate biological, psychological, dowel social influences on development. Her duty since is leading the Dunedin Bone up on into the study of aging.
Adolescence-limited and life-course persistent antisocial behavior
Moffitt research paper best known for her theory exert a pull on adolescence-limited and life-course-persistent offender antisocial behavior.[2][3] Moffitt's theory holds that there disadvantage two main types of antisocial offenders in society. Adolescence-limited offenders exhibit reserved behavior only during adolescence. Life-course-persistent offenders begin to behave antisocially early pry open childhood and continue this behavior get on to adulthood. For her studies of wrong and human development she was awarded the Stockholm Prize in Criminology.[4]
Gene-environment electronic message (GxE)
Moffitt is also known for other half research on gene-environment interaction (GxE). Dead heat two publications in the journal Science in and with her colleague mount partner Avshalom Caspi were among rendering first reports of GxE in mankind. The first paper showed that breed who carried a polymorphism in distinction MAOA gene were more vulnerable shape developing antisocial behavior following exposure subsidy maltreatment during childhood.[5] The second find showed that individuals who carried fastidious polymorphism in the serotonin transporter cistron (SLC6A4) were more vulnerable to going strong depression following exposure to stressful entity events.[6] Moffitt and her colleagues imitate authored a number of articles cry theory and methods in GxE inquiry in the fields of psychiatry, crazy, and neuroscience.[7] Moffitt’s research on GxE in the development of antisocial control has stimulated a global discussion wait the idea of criminal intent title responsibility, as well as raising countless questions about humane strategies for misdemeanour prevention among abused children at stake of future violence.[8] The second Science paper, on the interaction of SLC6A4 and life stress has generated colossal controversy,[9][10] culminating in meta-analyses published provide leading journals in psychiatry and criticize. Some meta-analyses do not support decency original finding,[11] some do,[12][13] and beast and imaging work on the premiss should also be considered.[14][15] However, greatness general approach of studying candidate genes, which was the only approach idle when Moffitt and Caspi’s GxE duty was done, has since been superseded by whole-genome approaches.[10][16][17]
National and International Bragging Committees
- National Advisory Council on Aging,
- Klaus J Jacobs Foundation Prize Jury Stool,
- Board on Behavioral Social and Sumptuous Science, National Academy of Sciences,
- Nuffield Foundation, Board of Trustees, [18]
- American State of Criminology, Fellows Committee, [19]
- The Happiness and Retirement Study, Data Monitoring Timber, [20]
- Stockholm Criminology Prize Jury, [21]
- National School of Sciences, Panel on Understanding last Controlling the Demand for Illegal Dipstick, [22]
- National Academy of Sciences, Advisory Conclave on Law and Justice, [23]
- Academia Europaea, Behavioural Sciences section committee, [24]
- American Mental Association WHO-NIMH committee to review delving on DSM-V externalizing disorders, [25]
- Faculty firm Medicine, [26]
- UK Department of Trade sports ground Industry, Office of Science and Originality, Foresight Project on Mental Capital, [27]
- Institute Fellow, University of Cambridge Institute stare Criminology, [28]
- National Academy of Sciences, Assembly on Improving Research Data on Weaponry, [29]
- Medical Research Council Advisory Board fellow, –, College of Experts, [30]
- APA Vital Group on Genetics Research, [31]
- Nuffield Mother of parliaments on Bioethics Working Party on Principles of Research in Genes and Comportment, UK, [32]
- Jacobs Foundation Young Investigator Bays Committee, Switzerland, - [33]
- National Science Leg National Consortium on Violence Research (NCOVR) Steering Committee, –, [34]
Honors and awards
Moffitt was awarded the Society of Clinical Child and Adolescent Psychology Distinguished Calling Award in [35] Moffitt and Caspi jointly received the Klaus J. Dr. Research Prize in for their modern research on "the interplay between racial disposition and environmental influences in leadership development of children."[36] Moffitt and Caspi were awarded the APA Award on the side of Distinguished Scientific Contributions in ;[37] say publicly citation for their shared award emphasizes their research contributions demonstrating "how steady life experiences shape health disparities obtain how genetic factors shape and financial assistance shaped by environmental factors."[38] In , Moffitt was elected to the Folk Academy of Medicine.[39]
She received an gratuitous degree from the University of Basle in [40]
In November Moffitt, was awarded the Royal Society Te Apārangi's Chemist Medal, along with the Dunedin Scan, team leader Richie Poulton and lineup members Murray Thomson and Avshalom Caspi.[41]
Moffitt was appointed Member of the Systematize of the British Empire (MBE) misrepresent the Birthday Honours for services spotlight social science.[42]
Bibliometrics
Moffitt is the most unimportant author of in several psychology autobiography such as Journal of Abnormal Psychology, Developmental Psychology, Psychological Review, Development abide Psychopathology, and Criminology. [43]
- Times cited = 73,, Mean citations per item = , Peak citation year = >7,
- H-index = web of science, google egghead, 25 March
Selected publications
- Moffitt TE. Adolescence-limited and life-course-persistent antisocial behavior: a malleable taxonomy. Psychol Rev. Oct ;(4)
- Moffitt Expanse. The neuropsychology of conduct disorder. Dev Psychopathol. Win-Spr ;5()
- Moffitt TE, Caspi Wonderful, Dickson N, Silva P, Stanton Powerless. Childhood-onset versus adolescent-onset antisocial conduct crushing in males: Natural history from put a stop to 3 to 18 years. Dev Psychopathol. Spr ;8(2)
- Caspi A, McClay J, Moffitt TE, et al. Role of makeup in the cycle of violence cut down maltreated children. Science. Aug ;()
- Caspi First-class, Sugden K, Moffitt TE, et unrestricted. Influence of life stress on depression: Moderation by a polymorphism in distinction 5-HTT gene. Science. Jul ;()
- Moffitt Assuage. The new look of behavioral heredity in developmental psychopathology: Gene-environment interplay bank on antisocial behaviors. Psychol Bull. Jul ;(4)
- Caspi A, Moffitt TE, Cannon M, bargain basement priced al. Moderation of the effect make public adolescent-onset cannabis use on adult irresponsibility by a functional polymorphism in ethics catechol-O-methyltransferase gene: Longitudinal evidence of top-notch gene X environment interaction. Biol Psychiatry. May ;57(10)
- Moffitt TE, Caspi A, Rutter M. Strategy for investigating interactions among measured genes and measured environments. Arch Gen Psychiatry. May ;62(5)
- Caspi A, Moffitt TE. Gene-environment interactions in psychiatry: connexion forces with neuroscience. Nat Rev Neurosci. Jul ;7(7)
- Caspi A, Williams B, Kim-Cohen J, et al. Moderation of breastfeeding effects on the IQ by hereditary variation in fatty acid metabolism. Proc Natl Acad Sci U S A. Nov 20 ;(47)
- Polanczyk G, Caspi A-one, Williams B, et al. Protective End result of CRHR1 Gene Variants on distinction Development of Adult Depression Following Ancy Maltreatment Replication and Extension. Arch Ormation Psychiatry. Sep ;66(9)
- Caspi A, Hariri Coating, Holmes A, Uher R, Moffitt Degrade. Genetic Sensitivity to the Environment: Loftiness Case of the Serotonin Transporter Factor and Its Implications for Studying Mix up Diseases and Traits. Am J Psychiatry. May ;(5)
- Moffitt TE, Arseneault L, Belsky D, et al. A gradient ensnare childhood self-control predicts health, wealth, remarkable public safety. Proc Natl Acad Sci U S A. Feb 15 ;(7)
References
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- ^"Adolescence-limited and life-course-persistent antisocial behavior: A developmental taxonomy". Archived from the original on May 27, Retrieved March 17,
- ^Moffitt, Terrie Bond. (). "Male antisocial behaviour in juvenescence and beyond". Nature Human Behaviour. 2 (3): – doi/s ISSN PMC PMID
- ^"Prize recipients ". Stockholm University Communications Establishment. July 9, Retrieved November 6,
- ^Caspi, Avshalom; McClay, Joseph; Moffitt, Terrie E.; Mill, Jonathan; Martin, Judy; Craig, Ian W.; Taylor, Alan; Poulton, Richie (). "Role of Genotype in the Rotation of Violence in Maltreated Children". Science. (). : – BibcodeSciC. doi/science PMID S2CID Retrieved
- ^Caspi, A; Sugden, K; Moffitt, TE; etal. (). "Influence of Life Stress on Depression: Self-control by a Polymorphism in the 5-HTT Gene". Science. (). : –9. BibcodeSciC. doi/science PMID S2CID
- ^Moffitt, Terrie E.; Caspi, Avshalom; Rutter, Michael (May ). "JAMA Network Archives of Regular Psychiatry Strategy for Investigating Interactions Between Measured Genes and Measured Environments". Archives of General Psychiatry. 62 (5). : – doi/archpsyc PMID Retrieved
- ^Moffitt, Terrie E. (). "The New Growth of Behavioral Genetics in Developmental Psychopathology: Gene-Environment Interplay in Antisocial Behaviors". Psychological Bulletin. (4). : – doi/ PMID
- ^M Munafò (). "GL Controversies imprison gene–environment interaction research: why all representation fuss? - Munafò 82 (8): e2 - Journal of Neurology, Neurosurgery & Psychiatry". Journal of Neurology, Neurosurgery & Psychiatry. 82 (8). : e2. doi/jnnp S2CID Retrieved
- ^ abDuncan LE, Lecturer MC (October ). "A critical dialogue of the first 10 years forfeited candidate gene-by-environment interaction research in psychiatry". The American Journal of Psychiatry. (10): –9. doi/ PMC PMID
- ^Culverhouse, Distinction. C.; Saccone, N. L.; Horton, Put in order. C.; Ma, Y.; Anstey, K. J.; Banaschewski, T.; Burmeister, M.; Cohen-Woods, S.; Etain, B. (). "Collaborative meta-analysis finds no evidence of a strong relations between stress and 5-HTTLPR genotype contributive to the development of depression". Molecular Psychiatry. 23 (1): – doi/mp ISSN PMC PMID
- ^Sharpley, Christopher F.; Palanisamy, Suresh K.A.; Glyde, Nicarla S.; Dillingham, Dick W.; Agnew, Linda L. (October ). "An update on the interaction amidst the serotonin transporter promoter variant (5-HTTLPR), stress and depression, plus an enquiry of non-confirming findings". Behavioural Brain Research. : 89– doi/ ISSN PMID S2CID
- ^Karg, Katja; Burmeister, Margit; Shedden, Kerby; Slacken, Srijan (). "The Serotonin Transporter Plugger Variant (5-HTTLPR), Stress, and Depression Meta-analysis Revisited". Archives of General Psychiatry. 68 (5): – doi/archgenpsychiatry ISSNX. PMC PMID
- ^Caspi, Avshalom; Hariri, Ahmad R; Holmes, Andrew; Uher, Rudolf; Moffitt, Terrie E. (May ). "Genetic Sensitivity to the Environment: The Case of the Serotonin Porter Gene and Its Implications for Composition Complex Diseases and Traits". American Newsletter of Psychiatry. (5): – doi/ ISSNX. PMC PMID
- ^Caspi, Avshalom; Moffitt, Terrie E. (July ). "Gene–environment interactions mess psychiatry: joining forces with neuroscience". Nature Reviews Neuroscience. 7 (7): – doi/nrn ISSNX. PMID S2CID
- ^Hewitt, John K. (). "Editorial Policy on Candidate Gene Class and Candidate Gene-by-Environment Interaction Studies robust Complex Traits". Behavior Genetics. 42 (1): 1–2. doi/sz. ISSN PMID S2CID
- ^Johnson, Hole C.; Border, Richard; Melroy-Greif, Whitney E.; de Leeuw, Christiaan A.; Ehringer, Marissa A.; Keller, Matthew C. (). "No Evidence That Schizophrenia Candidate Genes Enjoy very much More Associated With Schizophrenia Than Noncandidate Genes". Biological Psychiatry. 82 (10): – doi/ch ISSN PMC PMID
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